KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC2
All Species:
31.21
Human Site:
S248
Identified Species:
42.92
UniProt:
P06493
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06493
NP_001777.1
297
34081
S248
F
P
K
W
K
P
G
S
L
A
S
H
V
K
N
Chimpanzee
Pan troglodytes
XP_001164618
264
30384
H219
K
P
G
S
L
A
S
H
V
K
N
L
D
E
N
Rhesus Macaque
Macaca mulatta
XP_001095798
297
34077
S248
F
P
K
W
K
P
G
S
L
A
S
H
V
K
N
Dog
Lupus familis
XP_849450
297
34047
S248
F
P
K
W
K
P
G
S
L
A
S
H
V
K
N
Cat
Felis silvestris
Mouse
Mus musculus
P11440
297
34088
S248
F
P
K
W
K
P
G
S
L
A
S
H
V
K
N
Rat
Rattus norvegicus
P39951
297
34116
S248
F
P
K
W
K
P
G
S
L
A
S
H
V
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509674
303
34737
S248
F
P
K
W
K
P
G
S
L
A
S
H
V
K
N
Chicken
Gallus gallus
P13863
303
34670
S248
F
P
K
W
K
P
G
S
L
G
T
H
V
Q
N
Frog
Xenopus laevis
P24033
302
34513
S248
F
P
K
W
K
G
G
S
L
S
S
N
V
K
N
Zebra Danio
Brachydanio rerio
NP_997729
302
34539
N248
F
P
K
W
K
S
G
N
L
A
N
T
V
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
Q248
F
P
C
W
S
T
N
Q
L
T
N
Q
L
K
N
Honey Bee
Apis mellifera
XP_393093
585
68394
N535
F
P
N
W
I
T
N
N
L
E
S
Q
V
K
T
Nematode Worm
Caenorhab. elegans
P34556
332
38277
F266
F
P
K
W
R
E
N
F
L
R
D
K
F
Y
D
Sea Urchin
Strong. purpuratus
XP_781415
301
34665
N247
F
P
M
W
T
K
P
N
I
K
G
A
V
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
D248
F
P
R
W
Q
A
Q
D
L
A
T
V
V
P
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
D248
F
P
K
W
K
P
T
D
L
E
T
F
V
P
N
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
R253
K
P
S
F
P
Q
W
R
R
K
D
L
S
Q
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.5
99.3
98.6
N.A.
96.3
96.9
N.A.
95.3
90.4
84.7
81.4
N.A.
71.3
36.2
58.4
70.1
Protein Similarity:
100
88.8
99.6
99.6
N.A.
98.6
98.9
N.A.
96.6
94.3
93.3
91.7
N.A.
83.8
42.2
72.8
86.7
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
100
80
80
73.3
N.A.
40
46.6
33.3
33.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
100
93.3
93.3
86.6
N.A.
53.3
53.3
46.6
46.6
Percent
Protein Identity:
N.A.
63.3
N.A.
64.9
59
N.A.
Protein Similarity:
N.A.
78.7
N.A.
79.4
76.5
N.A.
P-Site Identity:
N.A.
46.6
N.A.
60
6.6
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
66.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
48
0
6
0
0
0
% A
% Cys:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
12
0
6
0
6
% D
% Glu:
0
0
0
0
0
6
0
0
0
12
0
0
0
6
0
% E
% Phe:
89
0
0
6
0
0
0
6
0
0
0
6
6
0
0
% F
% Gly:
0
0
6
0
0
6
53
0
0
6
6
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
42
0
0
0
% H
% Ile:
0
0
0
0
6
0
0
0
6
0
0
0
0
0
0
% I
% Lys:
12
0
65
0
59
6
0
0
0
18
0
6
0
65
0
% K
% Leu:
0
0
0
0
6
0
0
0
83
0
0
12
6
0
0
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
0
0
0
18
18
0
0
18
6
0
0
77
% N
% Pro:
0
100
0
0
6
48
6
0
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
6
6
6
6
0
0
0
12
0
12
0
% Q
% Arg:
0
0
6
0
6
0
0
6
6
6
0
0
0
0
0
% R
% Ser:
0
0
6
6
6
6
6
48
0
6
48
0
6
0
0
% S
% Thr:
0
0
0
0
6
12
6
0
0
6
18
6
0
0
6
% T
% Val:
0
0
0
0
0
0
0
0
6
0
0
6
77
0
6
% V
% Trp:
0
0
0
89
0
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _